A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25

A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25

Botulinum neurotoxin type-A (BoNT/A), as onabotulinumtoxinA, is approved globally for 11 major therapeutic and cosmetic indications. While the mechanism of action for BoNT/A at the presynaptic nerve terminal has been established, questions remain regarding intracellular trafficking patterns and over...

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Bibliographic Details
Main Authors: Catherine Rhéaume, Brian B. Cai, Joanne Wang, Ester Fernández-Salas, K. Roger Aoki, Joseph Francis, Ron S. Broide
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Toxins
Subjects:
botulinum neurotoxin
SNAP25
neuromuscular junction
motor nerve
autonomic nerve
recombinant antibody
Online Access:http://www.mdpi.com/2072-6651/7/7/2354

Internet

http://www.mdpi.com/2072-6651/7/7/2354

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