Cardiovascular action of insulin in health and disease: focus in endothelial L-arginine transport and cardiac voltage-dependent potassium channels.

Cardiovascular action of insulin in health and disease: focus in endothelial L-arginine transport and cardiac voltage-dependent potassium channels.

The impairment of insulin signaling on diabetes mellitus has been related to cardiovascular dysfunction, heart failure and sudden death. In human endothelium, cationic amino acid transporter 1 (hCAT-1) is related to the synthesis of nitric oxide (NO). Insulin has a vascular effect in endothelial cel...

Full description

Bibliographic Details
Main Authors: Sebastián eDubó, David eGallegos, Lissette eCabrera, Luis eSobrevia, Leandro Antonio Zuniga, Marcelo eGonzalez
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Physiology
Subjects:
Endothelium
Heart Failure
Insulin
Nitric Oxide
action potential
insulin resistance.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00074/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00074/full

Similar Items