Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif

Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network, whose role in altering gene expression remains unclear. Here, we study a common autoregulatory network motif, the negative single-input modu...

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Bibliographic Details
Main Authors: Md Zulfikar Ali, Vinuselvi Parisutham, Sandeep Choubey, Robert C Brewster
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/56517