Adjunctive antibacterial agents as a salvage therapy in relapsed vascular pythiosis patients

Human vascular pythiosis is a life-threatening condition caused by Pythium insidiosum. Patients with unresectable intra-abdominal artery involvement have not previously survived, despite being treated with antifungal agents and immunotherapy. We report two novel cases of intra-abdominal pythiosis in...

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Bibliographic Details
Main Authors: Nuttapon Susaengrat, Pattama Torvorapanit, Rongpong Plongla, Nipat Chuleerarux, Kasama Manothummetha, Jarruprot Tuangsirisup, Navaporn Worasilchai, Ariya Chindamporn, Nitipong Permpalung
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971219303583
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Summary:Human vascular pythiosis is a life-threatening condition caused by Pythium insidiosum. Patients with unresectable intra-abdominal artery involvement have not previously survived, despite being treated with antifungal agents and immunotherapy. We report two novel cases of intra-abdominal pythiosis in patients for whom surgery could not be performed, who were successfully treated with adjunctive antibacterial agents. Keywords: Vascular pythiosis, Azithromycin, Doxycycline, Clarithromycin, Voriconazole
ISSN:1201-9712