Evolution of innate immunity: clues from invertebrates via fish to mammals

Host responses against invading pathogens are basic physiological reactions of all living organisms. Since appearance of the first eukaryotic cells a series of defence mechanisms have evolved in order to secure cellular integrity, homeostasis and survival of the host. Invertebrates, ranging from pro...

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Bibliographic Details
Main Author: Kurt eBuchmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00459/full