Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance

Integrons ensure a rapid and “on demand” response to environmental stresses driving bacterial adaptation. They are able to capture, store, and reorder functional gene cassettes due to site-specific recombination catalyzed by their integrase. Integrons can be either sedentary and chromosomally locate...

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Bibliographic Details
Main Authors: Céline Loot, Aleksandra Nivina, Jean Cury, Joséé Antonio Escudero, Magaly Ducos-Galand, David Bikard, Eduardo P. C. Rocha, Didier Mazel, Julian E. Davies
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e02296-16