Phacolytic uveitis associated with spontaneous rupture of anterior capsule in a patient with Alport syndrome

• Main Authors: López Torres, Vanessa, Ramírez-Cheyne, Julián Andrés, Lozano Cruz, Edgar, Salamanca Libreros, Omar Fernando
• Format: Article
• Language: Spanish
• Published: Universidad de Antioquia 2019-04-01
• Series: Iatreia
• Subjects: Cataract; Lens Capsule; Lens Capsule; Hereditary; Nephritis; Uveitis
• Online Access: http://aprendeenlinea.udea.edu.co/revistas/index.php/iatreia/article/view/332321/20793212

Alport syndrome is a rare genetic disorder due to mutations involving the coding genes for type IV collagen characterized by renal failure, sensorineural hearing loss and ocular abnormalities. This article presents a 24-year-old man with one day of sudden decrease in visual acuity in left eye due to spontaneous rupture of anterior lens capsule, related to cataract, phacolytic uveitis and ocular hypertension. In the anamnesis, personal history of hearing loss, renal failure and two-family members with a clinical diagnosis of Alport syndrome were found. The inheritance map was suggestive of a dominant inheritance X-linked pattern. Topical treatment was initiated with prednisone, atropine and brimonidine/timolol. Subsequently, phacoemulsification and aspiration of lens residues was performed, obtaining clinical relief.