Distinctions between non-peptide angiotensin II AT1-receptor antagonists

Distinctions between non-peptide angiotensin II AT1-receptor antagonists

A far-reaching understanding of the molecular action mechanism of AT1-receptor antagonists (AIIAs) was obtained by using CHO cells expressing transfected human AT 1-receptors. In this model, direct [3H]-antagonist binding and inhibition of agonist-induced responses (inositol phosphate accumulation)...

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Bibliographic Details
Main Authors: Georges Vauquelin, Frederik LP Fierens, Ilse Verheijen, Patrick ML Vanderheyden
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2001-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/14703203010020010401

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