Identification of Specific Circular RNA Expression Patterns and MicroRNA Interaction Networks in Mesial Temporal Lobe Epilepsy

Identification of Specific Circular RNA Expression Patterns and MicroRNA Interaction Networks in Mesial Temporal Lobe Epilepsy

Circular RNAs (circRNAs) regulate mRNA translation by binding to microRNAs (miRNAs), and their expression is altered in diverse disorders, including cancer, cardiovascular disease, and Parkinson’s disease. Here, we compare circRNA expression patterns in the temporal cortex and hippocampus of patient...

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Bibliographic Details
Main Authors: Lachlan G. Gray, James D. Mills, Ashton Curry-Hyde, Sasha Devore, Daniel Friedman, Maria Thom, Catherine Scott, Roland D. Thijs, Eleonora Aronica, Orrin Devinsky, Michael Janitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
circular RNAs
microRNAs
epilepsy
mesial temporal lobe epilepsy
RNA-Seq
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.564301/full

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