The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

<p>Abstract</p> <p>Background</p> <p>Many members of the ETS-domain transcription factor family are important drivers of tumourigenesis. In this context, their activation by Ras-ERK pathway signaling is particularly relevant to the tumourigenic properties of many ETS-do...

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Bibliographic Details
Main Authors: Gulmann Christian, Downey Paul, Guo Baoqiang, Keld Richard, Ang Yeng S, Sharrocks Andrew D
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/313

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