GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway

GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway

Abstract Background Glucose-regulated protein 78 (GRP78) is a member of the HSP70 protein family and a key endoplasmic reticulum chaperone. It has been revealed to play important roles both in the maturation, folding and transport of proteins and in cellproliferation. However, its involvement in mil...

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Bibliographic Details
Main Authors: Ying Liu, Xuemei Wang, Zhen Zhen, Yanbo Yu, Youwen Qiu, Wensheng Xiang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Cellular & Molecular Biology Letters
Subjects:
Cyclin D1
GRP78
Bovine mammary epithelial cells
mTOR
SREBP-1c
Online Access:http://link.springer.com/article/10.1186/s11658-019-0181-x

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http://link.springer.com/article/10.1186/s11658-019-0181-x

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