18F-labeled tracers targeting fibroblast activation protein

18F-labeled tracers targeting fibroblast activation protein

Abstract Background Cancer-associated fibroblasts are found in the stroma of epithelial tumors. They are characterized by overexpression of the fibroblast activation protein (FAP), a serine protease which was already proven as attractive target for chelator-based theranostics. Unfortunately, the val...

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Bibliographic Details
Main Authors: Thomas Lindner, Annette Altmann, Frederik Giesel, Clemens Kratochwil, Christian Kleist, Susanne Krämer, Walter Mier, Jens Cardinale, Hans-Ulrich Kauczor, Dirk Jäger, Jürgen Debus, Uwe Haberkorn
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Fibroblast activating protein
Positron Emission Tomography
18F-AlF-FAPI-74
Online Access:https://doi.org/10.1186/s41181-021-00144-x

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