Integrating genome-wide association and eQTLs studies identifies the genes associated with age at menarche and age at natural menopause.

<h4>Objective</h4>An early onset of menarche and, later, menopause are well-established risk factors for the development of breast cancer and endometrial cancer. Although the largest GWASs have identified 389 independent signals for age at menarche (AAM) and 44 regions for age at menopau...

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Bibliographic Details
Main Authors: Gang Wang, Jian Lv, Xiaoxin Qiu, Yujun An
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213953