A Biophysical Insight of Camptothecin Biodistribution: Towards a Molecular Understanding of Its Pharmacokinetic Issues
Camptothecin (CPT) is a potent anticancer drug, and its putative oral administration is envisioned although difficult due to physiological barriers that must be overcome. A comprehensive biophysical analysis of CPT interaction with biointerface models can be used to predict some pharmacokinetic issu...
Main Authors: | Andreia Almeida, Eduarda Fernandes, Bruno Sarmento, Marlene Lúcio |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/6/869 |
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