Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension

Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension

Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (...

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Bibliographic Details
Main Authors: Nikolov A., Blazhev A., Tzekova M., Kostov K., Popovski N.
Format: Article
Language:English
Published: Sciendo 2019-02-01
Series:Acta Medica Bulgarica
Subjects:
diabetes mellitus
arterial hypertension
anti-elastin antibodies (igg, igm, iga)
microangiopathy
lipid indices
Online Access:https://doi.org/10.2478/amb-2019-0004
Description
Summary:Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (AEAbs) IgM, IgG and IgA. The aim of this study was to investigate the possible association between AEAbs, lipid indices and the development of microvascular complications.
ISSN:0324-1750

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