Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis

Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis

Invertebrates generally lack adaptive immunity and compensate for this with highly efficient innate immune machineries such as phagocytosis by hemocytes to eradicate invading pathogens. However, how extrinsically cued hemocytes marshal internal signals to accomplish phagocytosis is not yet fully und...

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Bibliographic Details
Main Authors: Yue Lin, Fan Mao, Nai-Kei Wong, Xiangyu Zhang, Kunna Liu, Minwei Huang, Haitao Ma, Zhiming Xiang, Jun Li, Shu Xiao, Yang Zhang, Ziniu Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
phagocytes
heparan sulfate proteoglycans (HSPGs)
focal adhesion kinase (FAK)
transcriptome
Crassostrea hongkongensis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00416/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00416/full

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