Stachyose Improves the Effects of Berberine on Glucose Metabolism by Regulating Intestinal Microbiota and Short-Chain Fatty Acids in Spontaneous Type 2 Diabetic KKAy Mice

Stachyose Improves the Effects of Berberine on Glucose Metabolism by Regulating Intestinal Microbiota and Short-Chain Fatty Acids in Spontaneous Type 2 Diabetic KKAy Mice

Berberine (BBR) has the beneficial effects of anti-inflammation, anti-bacteria, and anti-diabetes. The clinical application of BBR has been hindered by its poor gastrointestinal absorption. Stachyose (Sta), a prebiotic agent, improves the composition of gut microbiota and benefits for diabetes. We t...

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Bibliographic Details
Main Authors: Hui Cao, Caina Li, Lei Lei, Xing Wang, Shuainan Liu, Quan Liu, Yi Huan, Sujuan Sun, Zhufang Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
stachyose
berberine
gut microbiota
short-chain fatty acids
glucose metabolism
type 2 diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.578943/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.578943/full

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