Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia.

Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia.

It has been well established that schizophrenia patients display impaired NMDA receptor (NMDAR) functions as well as exacerbation of symptoms in response to NMDAR antagonists. Abnormal NMDAR signaling presumably contributes to cognitive deficits which substantially contribute to functional disabilit...

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Bibliographic Details
Main Authors: Baohu Ji, Xin Wang, Antonio Pinto-Duarte, Minjung Kim, Sorana Caldwell, Jared W Young, Margarita M Behrens, Terrence J Sejnowski, Mark A Geyer, Xianjin Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688895?pdf=render

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http://europepmc.org/articles/PMC3688895?pdf=render

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