Efficient and accurate causal inference with hidden confounders from genome-transcriptome variation data.

Mapping gene expression as a quantitative trait using whole genome-sequencing and transcriptome analysis allows to discover the functional consequences of genetic variation. We developed a novel method and ultra-fast software Findr for higly accurate causal inference between gene expression traits u...

Full description

Bibliographic Details
Main Authors: Lingfei Wang, Tom Michoel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005703