Microglial inhibitory mechanism of Coenzyme Q10 against Aβ (1-42) induced cognitive dysfunctions: possible behavioral, biochemical, cellular and histopathological alterations

Microglial inhibitory mechanism of Coenzyme Q10 against Aβ (1-42) induced cognitive dysfunctions: possible behavioral, biochemical, cellular and histopathological alterations

Rationale: Alzheimer’s disease (AD) is a debilitating disease with complex pathophysiology. Amyloid beta (Aβ) (1-42) is a reliable model of AD that recapitulates many aspects of human AD. Objective: The present study has been designed to investigate the neuroprotective potential of Coenzyme Q10 (CoQ...

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Bibliographic Details
Main Authors:	Arti eSingh, Anil eKumar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-11-01
Series:	Frontiers in Pharmacology
Subjects:	Minocycline Oxidative Stress Alzheimer’s disease Mitochondrial dysfunction Neuroinflammation coenzyme Q10
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00268/full

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