Investigating the role of islet cytoarchitecture in its oscillation using a new beta-cell cluster model.
The oscillatory insulin release is fundamental to normal glycemic control. The basis of the oscillation is the intercellular coupling and bursting synchronization of beta cells in each islet. The functional role of islet beta cell mass organization with respect to its oscillatory bursting is not wel...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1991600?pdf=render |