Comparison of Hemoglobin A1c Levels in Healthy Patients and Non Diabetic Iron Deficiency Anemia(IDA) Patients Before and after Intervention in Rafsanjan

• Main Authors: Z Sharif Zadeh Yazdi, A khodadadi-Zadeh, B Shidi-Zandi, F Mohseni Moghadam
• Format: Article
• Language: fas
• Published: Shahid Sadoughi University of Medical Sciences 2009-01-01
• Series: Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
• Subjects: Hb A1c; Iron Deficiency Anemia; Diabetes
• Online Access: http://85.185.157.11:6280/jssu/browse.php?a_id=603&slc_lang=en&sid=1&ftxt=1
• ISSN: 2228-5741; 2228-5733

Introduction: Glycemia and blood glucose levels are under the effect of Hb A1c and therefore they could be considered as a valid index for the follow-up and control of diabetes .There are different and controversial reports on the effects of iron deficiency anemia on Hb A1c. Effects of IDA in non diabetic patients are also unknown. The aim of the study was the comparison of Hb A1C levels in healthy patients and non diabetic Iron deficiency anemia (IDA) patients before and after intervention in Rafsanjan. Methods: This research was a semi– experimental intervention study. The population under study consisted of 30 non diabetic IDA patients and 30 healthy patients in Rafsanjan that were matched for age and sex and other characteristics. Ferritin, Hb, HCT, MCV, MCH, MCHC, FBS, BS 2HPP and Hb A1c, were measured to confirm IDA. These parameters were also measured in the healthy subjects (control group) to confirm their health and them being non diabetic and iron sufficient and all parameters were compared after the intervention. Then all patients with IDA were treated with iron; 6mg/ kg for 3 months. The tests was repeated again and results compared with the results of both the groups before the intervention. Results: The mean Hb A1c level before iron treatment was (7.64±2.08) in patients with IDA that was higher than the control group (5.97± 1.01)(p<0.05). Hb A1c decreased after iron therapy in patients with IDA. Conclusion: It is recommended that before any diagnostic or therapeutic decisions are made with regards to Hb A1c, iron deficiency should be corrected.