Liver-derived ketone bodies are necessary for food anticipation
Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with ß-hydroxybutyrate production and its subsequent pro...
Main Authors: | Rohit Chavan, Céline Feillet, Sara S. Fonseca Costa, James E. Delorme, Takashi Okabe, Jürgen A. Ripperger, Urs Albrecht |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10580 |
Similar Items
-
The Hepatic Monocarboxylate Transporter 1 (MCT1) Contributes to the Regulation of Food Anticipation in Mice
by: Tomaz Martini, et al.
Published: (2021-04-01) -
REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6
by: Rohit Chavan, et al.
Published: (2017-01-01) -
Regulation of Ketone Body and Coenzyme A Metabolism in Liver
by: Deng, Shuang
Published: (2011) -
Studies on the influence of phenethylbiguanide on ketone-body formation in rat liver /
by: Saini, Veena Chaudhri
Published: (1965) -
The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation
by: Brandon Podyma, et al.
Published: (2020-01-01)