Apoptotic Effect of Phosphatidylinositol 3-Kinase Inhibition on Acute Lymphoblastic Leukemia Cells Using Buparlisib

BACKGROUND AND OBJECTIVE: Resistance to chemotherapy is one of the most important problems in treatment of patients diagnosed with acute lymphoblastic leukemia (ALL). Pathway interruption of the phosphatidylinositol -3 kinase (PI3K) and its relation to resistance phenomena cause the inhibitors of th...

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Bibliographic Details
Main Authors: MR Sadri, A Safaroghli Azar, AR Kazemi, M Hamidpour, M Allahbakhshian Frasani, D Bashash
Format: Article
Language:English
Published: Babol University of Medical Sciences 2017-05-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Online Access:http://jbums.org/browse.php?a_code=A-10-3023-1&slc_lang=en&sid=1