Simultaneous determination of first-line anti-tuberculosis drugs and one metabolite of isoniazid by liquid chromatography/tandem mass spectrometry in patients with human immunodeficiency virus-tuberculosis coinfection

The incidence rate of tuberculosis (TB) in patients with human immunodeficiency virus (HIV) infection is 26 times higher than that in other patients. Patients with both infections require long-term combination therapy, which increases therapy complexity and might lead to serious adverse reactions an...

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Bibliographic Details
Main Authors: Yaru Xing, Lin Yin, Xiaoqin Le, Jun Chen, Lin Zhang, Yingying Li, Hongzhou Lu, Lijun Zhang
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021016352