Hemotransfusion and mechanical ventilation time are associated with intra-hospital mortality in patients with traumatic brain injury admitted to intensive care unit

• Main Authors: Kelson James Almeida, Ânderson Batista Rodrigues, Luiz Euripedes Almondes Santana Lemos, Marconi Cosme Soares de Oliveira Filho, Brisa Fideles Gandara, Raissa da Rocha Lopes, Daniel Rocha e Silva Modesto, Irizon Klecio Pereira Rego
• Format: Article
• Language: English
• Published: Academia Brasileira de Neurologia (ABNEURO) 2016-08-01
• Series: Arquivos de Neuro-Psiquiatria
• Subjects: traumatismos craniocerebrais; unidades de terapia intensiva; serviço de hemoterapia; desmame do respirador
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000800644&lng=en&tlng=en

ABSTRACT Objective To identify the factors associated with the intra-hospital mortality in patients with traumatic brain injury (TBI) admitted to intensive care unit (ICU). Methods The sample included patients with TBI admitted to the ICU consecutively in a period of one year. It was defined as variables the epidemiological characteristics, factors associated with trauma and variables arising from clinical management in the ICU. Results The sample included 87 TBI patients with a mean age of 28.93 ± 12.72 years, predominantly male (88.5%). The intra-hospital mortality rate was of 33.33%. The initial univariate analysis showed a significant correlation of intra-hospital death and the following variables: the reported use of alcohol (p = 0.016), hemotransfusion during hospitalization (p = 0.036), and mechanical ventilation time (p = 0.002). Conclusion After multivariate analysis, the factors associated with intra-hospital mortality in TBI patients admitted to the intensive care unit were the administration of hemocomponents and mechanical ventilation time.