Protective Effects of Purple Rice Husk against Diabetic Nephropathy by Modulating PGC-1α/SIRT3/SOD2 Signaling and Maintaining Mitochondrial Redox Equilibrium in Rats

Protective Effects of Purple Rice Husk against Diabetic Nephropathy by Modulating PGC-1α/SIRT3/SOD2 Signaling and Maintaining Mitochondrial Redox Equilibrium in Rats

Diabetic nephropathy (DN) is the primary cause of end-stage renal disease worldwide. Oxidative stress and mitochondrial dysfunction are central to its pathogenesis. Rice husk, the leftover from the milling process, is a good source of phytochemicals with antioxidant activity. This study evaluated th...

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Bibliographic Details
Main Authors: Orawan Wongmekiat, Narissara Lailerd, Anongporn Kobroob, Wachirasek Peerapanyasut
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
diabetes
kidney
mitochondria
<i>Oryza sativa</i>
oxidative stress
rice husk
Online Access:https://www.mdpi.com/2218-273X/11/8/1224

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