Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells

Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells

Autophagy is a homeostatic and inducible process affecting multiple aspects of the immune system. This intrinsic cellular process is involved in MHC-antigen (Ag) presentation, inflammatory signaling, cytokine regulation, and cellular metabolism. In the context of T cell responses, autophagy has an i...

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Bibliographic Details
Main Authors: Seth D. Merkley, Cameron J. Chock, Xuexian O. Yang, James Harris, Eliseo F. Castillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
autophagy
T cells
macrophages
inflammation
immunometabolism
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02914/full

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