Application of Size and Maturation Functions to Population Pharmacokinetic Modeling of Pediatric Patients

Application of Size and Maturation Functions to Population Pharmacokinetic Modeling of Pediatric Patients

Traditionally, dosage for pediatric patients has been optimized using simple weight-scaled methods, but these methods do not always meet the requirements of children. To overcome this discrepancy, population pharmacokinetic (PK) modeling of size and maturation functions has been proposed. The main o...

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Bibliographic Details
Main Authors: Hyun-moon Back, Jong Bong Lee, Nayoung Han, Sungwoo Goo, Eben Jung, Junyeong Kim, Byungjeong Song, Sook Hee An, Jung Tae Kim, Sandy Jeong Rhie, Yoon Sun Ree, Jung-woo Chae, JaeWoo Kim, Hwi-yeol Yun
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Pharmaceutics
Subjects:
size function
maturation function
pharmacometrics
pediatrics
cyclosporin
phenobarbital
vancomycin
Online Access:https://www.mdpi.com/1999-4923/11/6/259

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https://www.mdpi.com/1999-4923/11/6/259

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