Exploration of Aspergillus fumigatus Ras pathways for novel antifungal drug targets

Ras pathway signaling is a critical virulence determinant for pathogenic fungi. Localization of Ras to the plasma membrane (PM) is required for Ras network interactions supporting fungal growth and virulence. For example, loss of A. fumigatus RasA signaling at the PM via inhibition of palmitoylatio...

Full description

Bibliographic Details
Main Authors: Qusai eAl Abdallah, Jarrod R Fortwendel
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00128/full

Similar Items