Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over 600,000 people annually. Here, we report integrated computational and experimental investigations of the role and mechanisms of transcriptional regulation in cryptococcal infection. Major cryptococcal virulence tr...

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Bibliographic Details
Main Authors: Stacey R. Gish, Ezekiel J. Maier, Brian C. Haynes, Felipe H. Santiago-Tirado, Deepa L. Srikanta, Cynthia Z. Ma, Lucy X. Li, Matthew Williams, Erika C. Crouch, Shabaana A. Khader, Michael R. Brent, Tamara L. Doering
Format: Article
Language:English
Published: American Society for Microbiology 2016-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/2/e00313-16