Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion

Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion

Abstract Luteolin, a polyphenolic flavone, has been demonstrated to exert anti-tumor activity in various cancer types. Cisplatin drug resistance is a major obstacle in the management of ovarian cancer. In the present study, we investigated the chemo-sensitizing effect of luteolin in both cisplatin-r...

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Bibliographic Details
Main Authors: Haixia Wang, Youjun Luo, Tiankui Qiao, Zhaoxia Wu, Zhonghua Huang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Ovarian Research
Subjects:
Luteolin
Cisplatin-resistant ovarian cancer
Apoptosis
Migration
Invasion
Online Access:http://link.springer.com/article/10.1186/s13048-018-0468-y

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