Complement factor C4a does not activate protease‐activated receptor 1 (PAR1) or PAR4 on human platelets
Abstract Background Protease‐activated receptor (PAR) 1 and PAR4 are key thrombin signal mediators for human platelet activation and aggregation in response to vascular injury. They are primarily activated by thrombin cleavage of the N‐terminus to expose a tethered ligand. In addition to the canonic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
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| Series: | Research and Practice in Thrombosis and Haemostasis |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rth2.12459 |