Extensive decoupling of metabolic genes in cancer.

Tumorigenesis requires the re-organization of metabolism to support malignant proliferation. We examine how the altered metabolism of cancer cells is reflected in the rewiring of co-expression patterns among metabolic genes. Focusing on breast and clear-cell kidney tumors, we report the existence of...

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Bibliographic Details
Main Authors: Ed Reznik, Chris Sander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4427321?pdf=render

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