Impact of vascular risk factors on the frequency of chronic renal failure

• Main Authors: Rubén González Tabares, Frank Abel Acosta González, Leydiana Trimiño Galindo
• Format: Article
• Language: Spanish
• Published: ECIMED 2020-08-01
• Series: Revista Cubana de Medicina Militar
• Subjects: insuficiencia renal crónica; obesidad; enfermedades no transmisibles; diabetes mellitus; hipertensión; hiperlipoproteinemias; enfermedades cardiovasculares
• Online Access: http://www.revmedmilitar.sld.cu/index.php/mil/article/view/627

Introduction: Chronic renal insufficiency is related to multiple vascular risk factors. The prevalence of these entities has increased in Cuba in recent decades, associated with population aging. Objective: To identify the relationship between chronic renal failure, diagnosed according to glomerular filtration stages, with vascular risk factors (obesity, high blood pressure, diabetes mellitus, hyperlipoproteinemia, smoking) and established cardiovascular disease. Methods: A descriptive, cross-sectional study was carried out in 2913 patients. General, anthropometric data, vascular risk factors, and hemochemistry were collected. Carriers of chronic renal insufficiency were considered those with glomerular filtration rate lower than 60 mL / min / 1.73 m2. The relationship between chronic renal insufficiency and vascular risk factors was identified using the Odds Ratio. The mean values of the hemochemical variables were compared with one-way ANOVA. Results: 10.8% of chronic renal insufficiency (15.3% in women) was found, its frequency increased with age and was associated with the selected risk factors (established cardiovascular disease: OR 3,58; hyperlipoproteinemia: OR 2,96; hypertension: OR 2,95; diabetes mellitus: OR 2,70 and obesity: OR 1,33). The frequency of chronic renal insufficiency as well as blood glucose, cholesterol, triglyceride and HbA1c levels increased with the sum of risk factors. Conclusions: chronic renal insufficiency was very frequent in this series. It prevailed in the female sex and in the most advanced age groups. A significant relationship with the selected risk factors was found, which was higher in patients with established cardiovascular disease.