Design and implementation of a custom next generation sequencing panel for selected vitamin D associated genes

Design and implementation of a custom next generation sequencing panel for selected vitamin D associated genes

Abstract Background Biologically active vitamin D has an important regulatory role within the genome. It binds the vitamin D receptor (VDR) in order to control the expression of a wide range of genes as well as interacting with the epigenome to modify chromatin and methylation status. Vitamin D defi...

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Bibliographic Details
Main Authors: Katherine Angela Benson, Sourabh Chand, Alexander Peter Maxwell, Laura Jane Smyth, Jill Kilner, Richard Borrows, Amy Jayne McKnight
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Research Notes
Subjects:
AmpliSeq
Association
Kidney
Next Generation Sequencing
NGS
Renal
Online Access:http://link.springer.com/article/10.1186/s13104-017-2664-z

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