Dasatinib Modulates Invasive and Migratory Properties of Canine Osteosarcoma and has Therapeutic Potential in Affected Dogs
BACKGROUND: This investigation sought to elucidate the relationship between hepatocyte growth factor (HGF)–induced metastatic behavior and the tyrosine kinase inhibitors (TKIs) crizotinib and dasatinib in canine osteosarcoma (OS). Preliminary evidence of an apparent clinical benefit from adjuvant th...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-08-01
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Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523315000224 |