Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

<p>Abstract</p> <p>Background</p> <p>Poly(ADP-ribose) polymerases (PARPs) catalyze the formation of poly(ADP-ribose) (pADPr), a post-translational modification involved in several important biological processes, namely surveillance of genome integrity, cell cycle progre...

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Bibliographic Details
Main Authors: Isabelle Maxim, Moreel Xavier, Gagné Jean-Philippe, Rouleau Michèle, Ethier Chantal, Gagné Pierre, Hendzel Michael J, Poirier Guy G
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Proteome Science
Online Access:http://www.proteomesci.com/content/8/1/22

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