Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018

Background: Both hospital-acquired infection (HAI) and cancer represents major health concerns worldwide, but there is a paucity of data describing HAI in Chinese cancer patients. The objective of this study is to demonstrate the prevalence, causative agents, antimicrobial use and risk factors for H...

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Main Authors: Guyu Huang, Qianqian Huang, Guoqiang Zhang, Hu Jiang, Zhen Lin
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Infection and Public Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034120304032
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spelling doaj-7706b17dffbf4e3a92a107f8d06612962020-12-05T04:19:44ZengElsevierJournal of Infection and Public Health1876-03412020-12-01131219811987Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018Guyu Huang0Qianqian Huang1Guoqiang Zhang2Hu Jiang3Zhen Lin4Department of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, ChinaCorresponding author at: Department of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, 71 Hedi Road, Qingxiu District, Nanning, Guangxi, 530021, China.; Department of Hospital Infection Prevention and Control, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, ChinaBackground: Both hospital-acquired infection (HAI) and cancer represents major health concerns worldwide, but there is a paucity of data describing HAI in Chinese cancer patients. The objective of this study is to demonstrate the prevalence, causative agents, antimicrobial use and risk factors for HAI in a cancer hospital in Southwestern China. Methods: We use the criteria of the Ministry of Health of the People's Republic of China to define hospital-acquired infections. One-day cross-sectional surveys were annually conducted from 2014 to 2018. Trained staff collected hospital-acquired infections, antimicrobial use and clinical characteristics data of inpatients. Multivariate logistic regression was used to determine the potential risk factors associated with HAIs. Results: Of the 6717 patients surveyed, there were 140 patients (2.1%, 95% confidence interval, 1.7–2.4%) with 144 distinct HAIs. Lower respiratory tract infections (47, 32.6%) and surgical-site infections (29, 20.1%) were the most common HAIs. Escherichia coli was the most common pathogen (29.6%). Risk factors for HAI included younger age (<18 years) or older age (>65 years), hospitalization in the intensive care unit, presence of central catheter and undergoing surgery in the previous 30 days. The overall prevalence of patients receiving antimicrobial agents was 15.2%. Conclusion: To control hospital-acquired infections in cancer patients, surveillance and prevention strategies to infections associated with central catheters or related to surgery should be augmented.http://www.sciencedirect.com/science/article/pii/S1876034120304032Hospital-acquired infectionPoint-prevalence surveyCancerChina
collection DOAJ
language English
format Article
sources DOAJ
author Guyu Huang
Qianqian Huang
Guoqiang Zhang
Hu Jiang
Zhen Lin
spellingShingle Guyu Huang
Qianqian Huang
Guoqiang Zhang
Hu Jiang
Zhen Lin
Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018
Journal of Infection and Public Health
Hospital-acquired infection
Point-prevalence survey
Cancer
China
author_facet Guyu Huang
Qianqian Huang
Guoqiang Zhang
Hu Jiang
Zhen Lin
author_sort Guyu Huang
title Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018
title_short Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018
title_full Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018
title_fullStr Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018
title_full_unstemmed Point-prevalence surveys of hospital-acquired infections in a Chinese cancer hospital: From 2014 to 2018
title_sort point-prevalence surveys of hospital-acquired infections in a chinese cancer hospital: from 2014 to 2018
publisher Elsevier
series Journal of Infection and Public Health
issn 1876-0341
publishDate 2020-12-01
description Background: Both hospital-acquired infection (HAI) and cancer represents major health concerns worldwide, but there is a paucity of data describing HAI in Chinese cancer patients. The objective of this study is to demonstrate the prevalence, causative agents, antimicrobial use and risk factors for HAI in a cancer hospital in Southwestern China. Methods: We use the criteria of the Ministry of Health of the People's Republic of China to define hospital-acquired infections. One-day cross-sectional surveys were annually conducted from 2014 to 2018. Trained staff collected hospital-acquired infections, antimicrobial use and clinical characteristics data of inpatients. Multivariate logistic regression was used to determine the potential risk factors associated with HAIs. Results: Of the 6717 patients surveyed, there were 140 patients (2.1%, 95% confidence interval, 1.7–2.4%) with 144 distinct HAIs. Lower respiratory tract infections (47, 32.6%) and surgical-site infections (29, 20.1%) were the most common HAIs. Escherichia coli was the most common pathogen (29.6%). Risk factors for HAI included younger age (<18 years) or older age (>65 years), hospitalization in the intensive care unit, presence of central catheter and undergoing surgery in the previous 30 days. The overall prevalence of patients receiving antimicrobial agents was 15.2%. Conclusion: To control hospital-acquired infections in cancer patients, surveillance and prevention strategies to infections associated with central catheters or related to surgery should be augmented.
topic Hospital-acquired infection
Point-prevalence survey
Cancer
China
url http://www.sciencedirect.com/science/article/pii/S1876034120304032
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