Transcriptome Profiling Reveals Pro-Inflammatory Cytokines and Matrix Metalloproteinase Activation in Zika Virus Infected Human Umbilical Vein Endothelial Cells

Transcriptome Profiling Reveals Pro-Inflammatory Cytokines and Matrix Metalloproteinase Activation in Zika Virus Infected Human Umbilical Vein Endothelial Cells

The deformities in the newborns infected with Zika virus (ZIKV) present a new potential public health threat to the worldwide community. Although ZIKV infection is mainly asymptomatic in healthy adults, infection during pregnancy can cause microcephaly and other severe brain defects and potentially...

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Bibliographic Details
Main Authors: Svetlana Khaiboullina, Timsy Uppal, Konstatin Kletenkov, Stephen Charles St. Jeor, Ekaterina Garanina, Albert Rizvanov, Subhash C. Verma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
Zika virus
inflammation
cytokines
cell permeability
matrix metalloproteinase
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00642/full

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