Expansion of the TLO gene family enhances the virulence of Candida species.

Expansion of the TLO gene family enhances the virulence of Candida species.

The TLO genes are a family of subtelomeric ORFs in the fungal pathogens Candida albicans and C. dubliniensis encoding a subunit of the Mediator complex homologous to Med2. The more virulent pathogen C. albicans has 15 copies of the gene whereas the less pathogenic species C. dubliniensis has only tw...

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Bibliographic Details
Main Authors: Peter R Flanagan, Jessica Fletcher, Hannah Boyle, Razvan Sulea, Gary P Moran, Derek J Sullivan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6054389?pdf=render

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