Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.

Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.

Wnt signaling plays an important role in developmental and stem cell biology. To test the hypothesis that temporary inhibition of Wnt signaling will enhance granulation tissue and promote angiogenesis in tissue repair, we employed a recently characterized small molecule Wnt inhibitor. Pyrvinium is a...

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Bibliographic Details
Main Authors:	Sarika Saraswati, Maria P Alfaro, Curtis A Thorne, James Atkinson, Ethan Lee, Pampee P Young
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-11-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2993965?pdf=render

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