| Summary: | The search for alternative drugs for treating inflammatory diseases of bacterial etiology in high yielding cows that do not cause antibiotic resistance and do not reduce the quality of the obtained products is an urgent task for veterinary obstetrics. As one of this remedy, the authors have tested ozonated flaxseed oil (OFO), obtained by bubbling flaxseed oil with an ozon-oxygen mixture for four hours by means of ceramic spray with the ozone concentration being 30 mg / liter. During the bacteriological studies, it was found out that a two-hour incubation of the drug with a bacterial culture inhibits the growth of Staphylococcus aureus and Escherichia coli at a dilution of 108 microbial bodies (m.b.) in ml, bacteria of the genus Citrobacter at a concentration of 106 m.b. and Streptococcus agalactiae at the dilution of 107 m.b. in ml. The therapeutic efficiency of OFO was evaluated on the basis of using it for the cows of the Kholmogory Holstein breed, with the signs of postpartum septic catarrhal endometritis. For this purpose, 2 groups of animals were formed on the basis of analogues. For treating the cows of the experimental group the OFO has been used, and the cows of the control group were treated with the antibiotic containing the drug tylosinocar. For 5 months of observation, all animals were fertilized in the control group, and in the group where OFO was used this number was 93.3 %. Moreover, in the experimental group 47 % of the cows were fertilized after the first insemination, which is 27 % more in comparison with the control group. The duration from calving to fertilization in the group where OFO was used averaged 104 days, which is 21 days less (P <0.05) compared to the control group. Studies have shown that the use of OFO did not lead to the inhibitors emergence in milk in the experimental group of cows.
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