Immunogenetic Association Underlying Severe COVID-19

Immunogenetic Association Underlying Severe COVID-19

SARS-CoV2 has caused the current pandemic of new coronavirus disease 2019 (COVID-19) worldwide. Clinical outcomes of COVID-19 illness range broadly from asymptotic and mild to a life-threatening situation. This casts uncertainties for defining host determinants underlying the disease severity. Recen...

Full description

Bibliographic Details
Main Authors:	Kendall McCoy, Autumn Peterson, Yun Tian, Yongming Sang
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	Vaccines
Subjects:	COVID-19 interferon signaling chemokine signaling genome-wide association epigenetic regulation
Online Access:	https://www.mdpi.com/2076-393X/8/4/700

Similar Items

Dysregulated Interferon Response Underlying Severe COVID-19
by: LeAnn Lopez, et al.
Published: (2020-12-01)

The MEK Inhibitors Trametinib and Cobimetinib Induce a Type I Interferon Response in Human Keratinocytes
by: Daniela Lulli, et al.
Published: (2017-10-01)

Epigenetic Evolution of ACE2 and IL-6 Genes: Non-Canonical Interferon-Stimulated Genes Correlate to COVID-19 Susceptibility in Vertebrates
by: Eric R. Sang, et al.
Published: (2021-01-01)

The Importance of Context: Uncovering Species- and Tissue-Specific Effects of Genetic Risk Variants for Type 2 Diabetes
by: Soren Krogsgaard Thomsen, et al.
Published: (2016-08-01)

Immunogenetics of chemokines in childhood asthma.
Published: (2004)

Plant abiotic stress challenges from the changing environment
by: Andy Pereira
Published: (2016-07-01)

Adaptive Fisher method detects dense and sparse signals in association analysis of SNV sets
by: Xiaoyu Cai, et al.
Published: (2020-04-01)

Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
by: Bogusław Nedoszytko, et al.
Published: (2020-07-01)

Does gene length play a role? — Transient regulation of Gcn5 histone acetyltransferase under stress conditions
by: Yongtao Xue-Franzén
Published: (2014-12-01)

Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts
by: Margaret M Parker, et al.
Published: (2019-07-01)

A Role of Variance in Interferon Genes to Disease Severity in COVID-19 Patients
by: Leonid Gozman, et al.
Published: (2021-09-01)

Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors
by: Divyanshu Malhotra, et al.
Published: (2018-06-01)

The Multi-Omics Architecture of Juvenile Idiopathic Arthritis
by: Xiaoyuan Hou, et al.
Published: (2020-10-01)

Genomic factors underlying sex differences in trauma-related disorders
by: Olga Y. Ponomareva, et al.
Published: (2021-05-01)

Virus-Targeted Transcriptomic Analyses Implicate Ranaviral Interaction with Host Interferon Response in Frog Virus 3-Infected Frog Tissues
by: Yun Tian, et al.
Published: (2021-07-01)

Interferon-gamma in leishmaniasis.
by: Peter Epeh Kima, et al.
Published: (2013-06-01)

Matrix Metalloproteases as Influencers of the Cells’ Social Media
by: Daniel Young, et al.
Published: (2019-08-01)

IFN signaling: how a non-canonical model led to the development of IFN mimetics
by: Howard M Johnson, et al.
Published: (2013-07-01)

"Erratum: Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells"
by: Joseph eLarkin
Published: (2014-03-01)

A concise history of genome-wide association studies
by: Bobby P. C. Koeleman, et al.
Published: (2013-01-01)

Epigenome-Wide Comparative Study Reveals Key Differences Between Mixed Connective Tissue Disease and Related Systemic Autoimmune Diseases
by: Elena Carnero-Montoro, et al.
Published: (2019-08-01)

Mechanisms of Regulation of the Chemokine-Receptor Network
by: Martin J. Stone, et al.
Published: (2017-02-01)

Novel directions in data pre-processing and genome-wide association study (GWAS) methodologies to overcome ongoing challenges
by: Zahra Mortezaei, et al.
Published: (2021-01-01)

Current State of Precision Medicine in Primary Systemic Vasculitides
by: Erkan Demirkaya, et al.
Published: (2019-12-01)

A Positive Feedback Amplifier Circuit That Regulates Interferon (IFN)-Stimulated Gene Expression and Controls Type I and Type II IFN Responses
by: Agata Michalska, et al.
Published: (2018-05-01)

The cell sets the tone
by: Jonna Alanko, et al.
Published: (2018-06-01)

Combining Random Forests and a Signal Detection Method Leads to the Robust Detection of Genotype-Phenotype Associations
by: Faisal Ramzan, et al.
Published: (2020-08-01)

CHAPTER 1. IMMUNOGENETICS: GENOME WIDE ASSOCIATION OF NON-PROGRESSIVE HIV AND VIRAL LOAD CONTROL: HLA GENES AND BEYOND
by: Sophie eLimou, et al.
Published: (2013-05-01)

Application of CRISPR-Cas9 Based Genome-Wide Screening Approaches to Study Cellular Signalling Mechanisms
by: Sumana Sharma, et al.
Published: (2018-03-01)

High Dose IFN-β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells
by: Kensei Kishimoto, et al.
Published: (2021-04-01)

Higher expression of monocyte chemotactic protein 1 in mild COVID-19 patients might be correlated with inhibition of Type I IFN signaling
by: Xueyan Xi, et al.
Published: (2021-01-01)

Redox-sensitive activation of CCL7 by BRG1 in hepatocytes during liver injury
by: Ming Kong, et al.
Published: (2021-10-01)

Genome-Wide Association Analyses Highlight the Potential for Different Genetic Mechanisms for Litter Size Among Sheep Breeds
by: Song-Song Xu, et al.
Published: (2018-04-01)

Integrative Genomic Analysis Predicts Regulatory Role of N6-Methyladenosine-Associated SNPs for Adiposity
by: Weimin Lin, et al.
Published: (2020-07-01)

An Analysis of Genome-Wide Association Studies to Produce Evidence Useful in Guiding Their Reporting and Synthesis
by: Yurkiewich, Alexander John
Published: (2012)

An Analysis of Genome-Wide Association Studies to Produce Evidence Useful in Guiding Their Reporting and Synthesis
by: Yurkiewich, Alexander John
Published: (2012)

An Analysis of Genome-Wide Association Studies to Produce Evidence Useful in Guiding Their Reporting and Synthesis
by: Yurkiewich, Alexander John
Published: (2012)

An Analysis of Genome-Wide Association Studies to Produce Evidence Useful in Guiding Their Reporting and Synthesis
by: Yurkiewich, Alexander John
Published: (2012)

Genetics of Obesity Traits: A Bivariate Genome-Wide Association Analysis
by: Yili Wu, et al.
Published: (2018-05-01)

CCL2 induces articular chondrocyte MMP expression through ERK and p38 signaling pathways
by: Helen Willcockson, et al.
Published: (2021-03-01)