Transformation with Artificial Chromosomes in Oxytricha trifallax and Their Applications

Oxytricha trifallax, like other ciliates, has separate germline and somatic nuclei. The diploid germline genome in the micronucleus is composed of long conventional chromosomes. The macronucleus contains a somatic genome which is naturally fragmented into thousands of kilobase-sized chromosomes. Her...

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Bibliographic Details
Main Authors: Derek M. Clay, Hoyon Kim, Laura F. Landweber
Format: Article
Language:English
Published: Oxford University Press 2019-10-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400298