Loss of voltage-gated proton channel Hv1 leads to diet-induced obesity in mice

ObjectiveThe voltage-gated proton channel Hv1 has been proposed to mediate NADPH oxidase (NOX) function by regulating intracellular pH during respiratory bursts. In our previous work, we showed that Hv1 is expressed in pancreatic β cells and positively regulates insulin secretion. Here, we investiga...

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Bibliographic Details
Main Authors: Huimin Pang, Jinwen Li, Hongyan Du, Yingtang Gao, Jili Lv, Yanxia Liu, Shu Jie Li
Format: Article
Language:English
Published: BMJ Publishing Group 2020-04-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/8/1/e000951.full

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