Loss of voltage-gated proton channel Hv1 leads to diet-induced obesity in mice
ObjectiveThe voltage-gated proton channel Hv1 has been proposed to mediate NADPH oxidase (NOX) function by regulating intracellular pH during respiratory bursts. In our previous work, we showed that Hv1 is expressed in pancreatic β cells and positively regulates insulin secretion. Here, we investiga...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-04-01
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Series: | BMJ Open Diabetes Research & Care |
Online Access: | https://drc.bmj.com/content/8/1/e000951.full |