ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXL

ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXL

Abstract Background Glioma is the most common primary brain tumor in adults with a poor prognosis. As a member of ARF subfamily GTPase, ARL2 plays a key role in regulating the dynamics of microtubules and mitochondrial functions. Recently, ARL2 has been identified as a prognostic and therapeutic tar...

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Bibliographic Details
Main Authors: Yulin Wang, Gefei Guan, Wen Cheng, Yang Jiang, Fengping Shan, Anhua Wu, Peng Cheng, Zongze Guo
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
ARL2
Glioma
AXL
Tumorgenecity
Brain cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4517-0

Internet

http://link.springer.com/article/10.1186/s12885-018-4517-0

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