CONCENTRATION OF FREE AND CONNECTED ZINC IN BLOOD OF PERSONS WITH VARIOUS STATUS OF SMOKING

• Main Authors: V. I. Shevtsova, А. А. Zuykova
• Format: Article
• Language: Russian
• Published: SINAPS LLC 2017-08-01
• Series: Arhivʺ Vnutrennej Mediciny
• Subjects: zinc; zinc pools; smoking status; pathogenetic changes
• Online Access: https://www.medarhive.ru/jour/article/view/681

Objective: due to the high prevalence of smoking among russians, as well as the important role of the enzymes containing zinc during the formation of pathogenic responses in chronic obstructive lung disease, the aim of the work was to study the concentrations of zinc pools in smokers and nonsmokers.Materials and Methods: The distribution of the groups of smokers, smokers and non-smokers (with and without in the near surroundings of smokers) was made after the analysis of a questionnaire, which included questions on the presence of chronic diseases, the status and experience of smoking, the number of daily cigarettes smoked and the fact inhalation second-hand smoke in the street, home or work; vital capacity was measured with a dry portable spirometer, measuring the concentration of zinc produced by calorimetry. Statistical processing is performed using Microsoft Excel 2010 and Statistica 6.0 software and the use of H-Kruskal-Wallis test. Results: It was shown that the lowest concentration of total and free zinc active intobacco smoking. Statistically significant differences (p = 0.0001) in the level of general, free and bound zinc in smokers, non-smokers and former smokers, passive, and the lack of significant differences in the overall level of zinc in individuals with and without smoking in the immediate vicinity. An inverse correlation between smoking index and concentrations of total and bound zinc.Conclusion: The total concentration of zinc and its poolscan be regarded as an indicator of the effect of smoking on the body.