The role of PSMD9 in human disease: future clinical and therapeutic implications

The role of PSMD9 in human disease: future clinical and therapeutic implications

PSMD9 was first characterized as a component of the PA700 proteasomal regulator, and was found to stimulate association of PA700 with the catalytic 20S proteasomal core to form the active 26S proteasome. It was also independently identified under the name “bridge-1” as a transcriptional co-activator...

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Bibliographic Details
Main Authors: Joanne L. Hopper, Natasha Begum, Laura Smith, Thomas A. Hughes
Format: Article
Language:English
Published: AIMS Press 2015-11-01
Series:AIMS Molecular Science
Subjects:
PSMD9
proteasome
bridge-1
PDX-1
NF-κB
Online Access:http://www.aimspress.com/Molecular/article/532/fulltext.html

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